A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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Halfway through his job, Cees Dekker reinvented himself. Following decades of hardcore physics, he shifted his target to ‘nanobiology’ within the change of your millennium. A phrase he coined himself, for a make a difference of actuality.
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination perform.
Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins
Our operate was promptly adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors made from one- and multi-walled carbon nanotubes in Used Physics Letters.
That could be a desire of mine and we set to work that has a scrumptious dose of naivety. This is certainly something that will probably produce spectacular leads to the for a longer period term, but that does not subject. You shouldn't only want to work within the issues of tomorrow, but additionally to the questions on the working day after tomorrow.’
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is the fact these elements alongside one another make up a residing procedure. The key of reported existence, I do think, lies inside the interactions, the interaction of Individuals molecules. The big concern regarding the origin of everyday living continues to be unanswered. How did we at any time evolve from simple molecules to the extremely sophisticated units we see right now? We do not know. I want to work on these kinds of significant, open inquiries.’
Nanopores characterize a sublime and functional Software to evaluate solitary molecules. We investigation novel detection modes with good-point out nanopores together with several tips on how to evaluate proteins with nanopores. Initiatives encompass the next:
The rotors harness Vitality from a nanoscale drinking water and ion movement that's created by a static chemical or electrochemical likely gradient within the nanopore, which are recognized through a salt gradient or used voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological conditions, suggesting solutions to setting up Electrical power-transducing motors at nanoscale interfaces.
Bulk-floor coupling identifies the mechanistic ceesdekker.net relationship between Min-protein patterns in vivo and in vitro
Testing pseudotopological and nontopological styles for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments
Mother nature Physics many thanks the anonymous reviewers for his or her contribution for the peer evaluation of the perform.
2005, discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-array conformational modifications in Mre11/DNA repair service complexes; and initial pressure measurements with a DNA molecule inside a nanopore
‘I'm pushed by wonder and concerns. On a fabric stage I come across responses in physics, but I experience my deepest happiness with God. That faith also drives my science And the way I handle men and women.